Not known Facts About phenobarbital sodium injection dailymed
Not known Facts About phenobarbital sodium injection dailymed
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pentobarbital will minimize the extent or effect of amlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Intramuscular Administration: IM injection with the sodium salts of barbiturates need to be made deeply into a large muscle, in addition to a volume of 5 mL should not be exceeded at Anybody website as a consequence of probable tissue irritation.
pentobarbital will lower the extent or effect of bosentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
pentobarbital will lessen the extent or effect of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
DOSAGE AND ADMINISTRATION Dosages of barbiturates must be individualized with total familiarity with their particular qualities and encouraged rate of administration.
pentobarbital will lessen the level or effect of ondansetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. No dosage adjustment for ondansetron is usually recommended for individuals on these drugs.
pentobarbital will minimize the level or effect of fentanyl intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on into a get more info reduce in fentanyl plasma concentrations, not enough efficacy or, potentially, improvement of the withdrawal syndrome within a patient who's got created Bodily dependence to fentanyl.
Elderly people may perhaps react to barbiturates with marked exhilaration, melancholy, and confusion. In a few individuals, barbiturates regularly make excitement as opposed to despair. Dosage really should be diminished from the elderly because these clients could possibly be a lot more delicate to barbiturates.
pentobarbital will minimize the extent or effect of dapsone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.
pentobarbital will reduce the extent or effect of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or effect of piroxicam by influencing hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unidentified.
pentobarbital will reduce the extent or effect of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.
pentobarbital will reduce the level or effect of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unfamiliar.
The sodium salt occurs as being a white, a little bitter powder and that is freely soluble in water and alcohol but nearly insoluble in benzene and ether.